Effect of statin treatment for familial hypercholesterolaemia on life assurance: results of consecutive surveys in 1990 and 2002.
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چکیده
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منابع مشابه
Efficacy of statins in familial hypercholesterolaemia: a long term cohort study
OBJECTIVE To determine the efficacy of statin treatment on risk of coronary heart disease in patients with familial hypercholesterolaemia. DESIGN Cohort study with a mean follow-up of 8.5 years. SETTING 27 outpatient lipid clinics. SUBJECTS 2146 patients with familial hypercholesterolaemia without prevalent coronary heart disease before 1 January 1990. MAIN OUTCOME MEASURES Risk of coro...
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(project number 95/29/04). The opinions expressed therein are those of the authors and not necessarily those of the NHS Executive. DM was supported in the preparation of this paper by an unconditional grant from Merck Sharpe and Dohme. SEH and HAWN acknowledge grants RG2000025 and RG93008 from the British Heart Foundation. of underdiagnosis of familial hypercholesterolaemia in routine practice:...
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Nine patients with heterozygous familial hypercholesterolaemia were treated for eight weeks with either 40 mg pravastatin or placebo under double blind conditions. Six patients received pravastatin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. Treatment with pravastatin resulted in a significant decrease in plasma cholesterol caused by a decrease in low ...
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عنوان ژورنال:
- BMJ
دوره 328 7438 شماره
صفحات -
تاریخ انتشار 2004